I
ICD-10
International Statistical Classification of Diseases and Related Health Problems, 10th Edition
ICD-O-3
International Classification of Diseases for Oncology, 3rd Edition
Ig
Immunoglobulin
Incidence
A measure of the number of new cases of a particular condition in a specific population within a specified period of time
IPI
International Prognostic Index
The International Prognostic Index (IPI) was developed to predict outcomes in patients with aggressive large cell lymphomas to inform treatment decisions. Based on five criteria, patients are classified into one of four risk groups– low (0-1 risk factors present), low-intermediate (2), intermediate-high (3) and high (4-5).
Used for: Large cell lymphomas, marginal zone lymphoma, Burkitt lymphoma
Reference: The International Non-Hodgkin’s Lymphoma Prognostic Factors Project. A Predictive Model for Aggressive Non-Hodgkin’s Lymphoma. N. Engl. J. Med. 329, 987–994 (1993)
IPS
International Prognostic Score
The International Prognostic Score (IPS) for classical Hodgkin lymphoma was developed to identify patients at a lower risk who may not need to be treated with intensive chemotherapy. A score is calculated from seven risk factors with each demographic factor or blood parameter adding one point if above the threshold so a higher score indicates higher risk.
Used for: Classical Hodgkin lymphoma
Reference: Hasenclever, D. et al. A Prognostic Score for Advanced Hodgkin’s Disease. N. Engl. J. Med. 339, 1506–1514 (1998)
IPSS
International Prognostic Scoring System
The International Prognostic Scoring System (IPSS) was designed to predict risk of both survival and progression to acute myeloid leukaemia to inform patient treatment and management decisions. Patients are classified into one of four groups based on levels of three risk factors – low, intermediate-1, intermediate-2 and high. You can find the calculator on on the Prognostics page.
Used for: Myelodysplastic syndromes
Reference: Greenberg, P. et al. International Scoring System for Evaluating Prognosis in Myelodysplastic Syndromes. Blood 89, 2079–2088 (1997)
IPSS-R
Revised International Prognostic Scoring System
The Revised International Prognostic Scoring System (IPSS-R) builds on the International Prognostic Scoring System to predict progression of acute myeloid leukaemia and survival from MDS. It adds two additional risk factors to the three in the IPSS and classifies patients into one of five risk groups: very low, low, intermediate, high and very high.
Used for: Myelodysplastic syndromes
Reference: Greenberg, P. L. et al. Revised International Prognostic Scoring System for Myelodysplastic Syndromes. Blood 120, 2454–2465 (2012)
ISS
International Staging System