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Molecular diagnostics

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Displaying 16 results from 16 total publications.

Bewicke-Copley et al. 2022.

Longitudinal expression profiling identifies a poor risk subset of patients with ABC-type Diffuse Large B Cell Lymphoma

Findlay Bewicke-Copley,  Koorosh Korfi,  Shamza Araf,  Brendan Hodkinson,  Emil Kumar,  Thomas Cummin,  Margaret Ashton-Key,  Sharon L Barrans,  Suzan JL van Hoppe,  Cathy Burton,  Mohamed Elshiekh,  Simon Rule,  Nicola Crosbie,  Andrew James Clear,  Maria Calaminici,  Hendrik Friedrich Peter Runge,  Robert K Hills,  David W. Scott,  Lisa M Rimsza,  Geetha Menon,  Chulin Sha,  John Davies,  Ai Nagano,  Andrew John Davies,  Daniel Painter,  Alexandra Smith,  John G Gribben,  Kikkeri N Naresh,  David Robert Westhead,  Jessica Okosun,  Andrew J Steele,  Daniel J Hodson,  Sriram Balasubramanian,  Peter W. M. Johnson,  Jun Wang,  Jude Fitzgibbon.

Blood Advances
Pages: bloodadvances.2022007536.

Crouch et al. 2022.

Molecular subclusters of follicular lymphoma: a report from the UK's Haematological Malignancy Research Network

Simon Crouch,  Daniel Painter,  Sharon L. Barrans,  Eve Roman,  Philip A Beer,  Susanna L Cooke,  Paul Glover,  Suzan JL Van Hoppe,  Nichola Webster,  Stuart E Lacy,  Camilo Ruiz,  Peter J Campbell,  Daniel J Hodson,  Russell Patmore,  Cathy Burton,  Alexandra Smith,  Reuben M Tooze.

Blood Advances

Vries et al. 2022.

Genomic and microenvironmental landscape of stage I follicular lymphoma, compared to stage III/IV.

G. Tjitske Los-de Vries,  Wendy B. C. Stevens,  Erik van Dijk,  Carole Langois-Jacques,  Andrew J. Clear,  Phylicia Stathi,  Margaretha G. M. Roemer,  Matias Mendeville,  Nathalie J. Hijmering,  Birgitta Sander,  Andreas Rosenwald,  Maria Calaminici,  Eva Hoster,  Wolfgang Hiddemann,  Philippe Gaulard,  Gilles Salles,  Heike Horn,  Wolfram Klapper,  Luc Xerri,  Catherine Burton,  Reuben M. Tooze,  Alexandra G. Smith,  Christian Buske,  David W. Scott,  Yasodha Natkunam,  Ranjana Advani,  Laurie H. Sehn,  John Raemaekers,  John Gribben,  Eva Kimby,  Marie José Kersten,  Delphine Maucort-Boulch,  Bauke Ylstra,  Daphne de Jong.

Blood Advances

Gong et al. 2021.

Sequential inverse dysregulation of the RNA helicases DDX3X and DDX3Y facilitates MYC-driven lymphomagenesis

Chun Gong,  Joanna A. Krupka,  Jie Gao,  Nicholas F. Grigoropoulos,  George Giotopoulos,  Ryan Asby,  Michael Screen,  Zelvera Usheva,  Francesco Cucco,  Sharon Barrans,  Daniel Painter,  Nurmahirah Binte Mohammed Zaini,  Björn Haupl,  Susanne Bornelöv,  Igor Ruiz De Los Mozos,  Wei Meng,  Peixun Zhou,  Alex E. Blain,  Sorcha Forde,  Jamie Matthews,  Michelle Guet Khim Tan,  G. A. Amos Burke,  Siu Kwan Sze,  Philip Beer,  Cathy Burton,  Peter Campbell,  Vikki Rand,  Suzanne D. Turner,  Jernej Ule,  Eve Roman,  Reuben Tooze,  Thomas Oellerich,  Brian J. Huntly,  Martin Turner,  Ming-Qing Du,  Shamith A. Samarajiwa,  Daniel J. Hodson.

Molecular Cell
Volume: 81, Issue: 19, Pages: 4059-4075.e11.

Watad et al. 2021.

Somatic Mutations and the Risk of Undifferentiated Autoinflammatory Disease in MDS: An Under-Recognized but Prognostically Important Complication

Abdulla Watad,  Mark Kacar,  Nicola Luigi Bragazzi,  Qiao Zhou,  Miriam Jassam,  Jan Taylor,  Eve Roman,  Alexandra Smith,  Richard A. Jones,  Howard Amital,  Catherine Cargo,  Dennis McGonagle,  Sinisa Savic.

Frontiers in Immunology
Volume: 12.

Runge et al. 2020.

Application of the LymphGen classification tool to 928 clinically and genetically-characterised cases of diffuse large B cell lymphoma (DLBCL)

Hendrik F. P. Runge,  Stuart Lacy,  Sharon Barrans,  Philip A. Beer,  Daniel Painter,  Alexandra Smith,  Eve Roman,  Cathy Burton,  Simon Crouch,  Reuben Tooze,  Daniel J. Hodson.

British Journal of Haematology
Volume: 192, Issue: 1.

Bernard et al. 2020.

Implications of TP53 allelic state for genome stability, clinical presentation and outcomes in myelodysplastic syndromes

Elsa Bernard,  Yasuhito Nannya,  Robert P. Hasserjian,  Sean M. Devlin,  Heinz Tuechler,  Juan S. Medina-Martinez,  Tetsuichi Yoshizato,  Yusuke Shiozawa,  Ryunosuke Saiki,  Luca Malcovati,  Max F. Levine,  Juan E. Arango,  Yangyu Zhou,  Francesc Solé,  Catherine A. Cargo,  Detlef Haase,  Maria Creignou,  Ulrich Germing,  Yanming Zhang,  Gunes Gundem,  Araxe Sarian,  Arjan A. van de Loosdrecht,  Martin Jädersten,  Magnus Tobiasson,  Olivier Kosmider,  Matilde Y. Follo,  Felicitas Thol,  Ronald F. Pinheiro,  Valeria Santini,  Ioannis Kotsianidis,  Jacqueline Boultwood,  Fabio P. S. Santos,  Julie Schanz,  Senji Kasahara,  Takayuki Ishikawa,  Hisashi Tsurumi,  Akifumi Takaori-Kondo,  Toru Kiguchi,  Chantana Polprasert,  John M. Bennett,  Virginia M. Klimek,  Michael R. Savona,  Monika Belickova,  Christina Ganster,  Laura Palomo,  Guillermo Sanz,  Lionel Ades,  Matteo Giovanni Della Porta,  Alexandra G. Smith,  Yesenia Werner,  Minal Patel,  Agnès Viale,  Katelynd Vanness,  Donna S. Neuberg,  Kristen E. Stevenson,  Kamal Menghrajani,  Kelly L. Bolton,  Pierre Fenaux,  Andrea Pellagatti,  Uwe Platzbecker,  Michael Heuser,  Peter Valent,  Shigeru Chiba,  Yasushi Miyazaki,  Carlo Finelli,  Maria Teresa Voso,  Lee-Yung Shih,  Michaela Fontenay,  Joop H. Jansen,  José Cervera,  Yoshiko Atsuta,  Norbert Gattermann,  Benjamin L. Ebert,  Rafael Bejar,  Peter L. Greenberg,  Mario Cazzola,  Eva Hellström-Lindberg,  Seishi Ogawa,  Elli Papaemmanuil.

Nature Medicine
Volume: 26, Pages: 1549-1556.

Lacy et al. 2020.

Targeted sequencing in DLBCL, molecular subtypes, and outcomes: a Haematological Malignancy Research Network report

Stuart E. Lacy,  Sharon L. Barrans,  Philip A. Beer,  Daniel Painter,  Alexandra G. Smith,  Eve Roman,  Susanna L. Cooke,  Camilo Ruiz,  Paul Glover,  Suzan J. L. Van Hoppe,  Nichola Webster,  Peter J. Campbell,  Reuben M. Tooze,  Russell Patmore,  Cathy Burton,  Simon Crouch,  Daniel J. Hodson.

Blood
Volume: 135, Issue: 20, Pages: 1759-1771.

Cucco et al. 2019.

Distinct genetic changes reveal evolutionary history and heterogeneous molecular grade of DLBCL with MYC/BCL2 double-hit

Francesco Cucco,  Sharon Barrans,  Chulin Sha,  Alexandra Clipson,  Simon Crouch,  Rachel Dobson,  Zi Chen,  Joe Sneath Thompson,  Matthew A. Care,  Thomas Cummin,  Josh Caddy,  Hongxiang Liu,  Anne Robinson,  Anna Schuh,  Jude Fitzgibbon,  Daniel Painter,  Alexandra Smith,  Eve Roman,  Reuben Tooze,  Catherine Burton,  Andrew J. Davies,  David R. Westhead,  Peter W. M. Johnson,  Ming-Qing Du.

Leukemia

Rosenwald et al. 2019.

Prognostic Significance of MYC Rearrangement and Translocation Partner in Diffuse Large B-Cell Lymphoma: A Study by the Lunenburg Lymphoma Biomarker Consortium

Andreas Rosenwald,  Susanne Bens,  Ranjana Advani,  Sharon Barrans,  Christiane Copie-Bergman,  Mad-Helenie Elsensohn,  Yaso Natkunam,  Maria Calaminici,  Birgitta Sander,  Maryse Baia,  Alexandra Smith,  Daniel Painter,  Luu Pham,  Shuchun Zhao,  Marita Ziepert,  Ekaterina S. Jordanova,  Thierry J. Molina,  Marie José Kersten,  Eva Kimby,  Wolfram Klapper,  John Raemaekers,  Norbert Schmitz,  Fabrice Jardin,  Wendy B. C. Stevens,  Eva Hoster,  Anton Hagenbeek,  John G. Gribben,  Reiner Siebert,  Randy D. Gascoyne,  David W. Scott,  Philippe Gaulard,  Gilles Salles,  Catherine Burton,  Daphne de Jong,  Laurie H. Sehn,  Delphine Maucort-Boulch.

Journal of Clinical Oncology

Cargo et al. 2019.

The use of targeted sequencing and flow cytometry to identify patients with a clinically significant monocytosis

Catherine Cargo,  Matthew Cullen,  Jan Taylor,  Mike Short,  Paul Glover,  Suzan Van Hoppe,  Alex Smith,  Paul Evans,  Simon Crouch.

Blood
Pages: blood-2018-08-867333.

Painter et al. 2018.

Cell-of-origin in diffuse large B-cell lymphoma: findings from the UK's population-based Haematological Malignancy Research Network

Daniel Painter,  Sharon Barrans,  Stuart Lacy,  Alexandra Smith,  Simon Crouch,  David Westhead,  Chulin Sha,  Russell Patmore,  Reuben Tooze,  Cathy Burton,  Eve Roman.

British Journal of Haematology
Volume: 185, Issue: 4, Pages: 781-784.

Cargo et al. 2015.

Targeted sequencing identifies patients with preclinical MDS at high risk of disease progression

Catherine A. Cargo,  Nicola Rowbotham,  Paul A. Evans,  Sharon L. Barrans,  David T. Bowen,  Simon Crouch,  Andrew S. Jack.

Blood
Volume: 126, Issue: 21, Pages: 2362-2365.

Clipson et al. 2015.

The prognosis of MYC translocation positive diffuse large B-cell lymphoma depends on the second hit

Alexandra Clipson,  Sharon Barrans,  Naiyan Zeng,  Simon Crouch,  Nicholas F Grigoropoulos,  Hongxiang Liu,  Sylvia Kocialkowski,  Ming Wang,  Yuanxue Huang,  Lisa Worrillow,  John Goodlad,  Jenny Buxton,  Michael Neat,  Paul Fields,  Bridget Wilkins,  John W Grant,  Penny Wright,  Hesham EI-Daly,  George A Follows,  Eve Roman,  A James Watkins,  Peter W M Johnson,  Andrew Jack,  Ming-Qing Du.

The Journal of Pathology: Clinical Research
Volume: 1, Issue: 3, Pages: 125-133.

Barrans et al. 2012.

Whole genome expression profiling based on paraffin embedded tissue can be used to classify diffuse large B-cell lymphoma and predict clinical outcome

S.L. Barrans,  S. Crouch,  M.A. Care,  L. Worrillow,  A. Smith,  R. Patmore,  D.R. Westhead,  R. Tooze,  E. Roman,  A.S. Jack.

British Journal of Haematology
Volume: 159, Issue: 4, Pages: 441-453.

Barrans et al. 2010.

Rearrangement of MYC is associated with poor prognosis in patients with diffuse large B-Cell lymphoma treated in the era of Rituximab

S. Barrans,  S. Crouch,  A. Smith,  K. Turner,  R. Owen,  R. Patmore,  E. Roman,  A. Jack.

Journal of Clinical Oncology
Volume: 28, Issue: 10, Pages: 3360-3365.